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Celution™ Breast Augmentation

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brestAdvanced Technologies for Breast Augmentation / How to Build a New Breast

An advanced procedure for breast augmentation based on regenerative medicine and involves the collection of stem cells from adipose tissue and the injection of those cells, together with adipose tissue, to allow semi-permanent maintenance of breast conditions after injection.






The Celution™ System is certified under ISO 10993,

an international standard for evaluation of the biocompatibility of medical devices.


Cytori_lableCytori_San_Diego_Enes_Celution













Celution1cytori_systemConventional breast augmentation procedures include fat injection, hyaluronic acid (Sub-Q) injection, and insertion of a bag prosthesis (artificial bag).

Celution™ Breast Augmentation
(transplantation of adipose tissue-derived stem cells) is a procedure for breast augmentation based on regenerative medicine and involves the collection of stem cells from adipose tissue and the injection of those cells, together with adipose tissue, to allow semi-permanent maintenance of breast conditions after injection.

In breast augmentation by Celution™ Breast Augmentation (transplantation of adipose tissue-derived stem cells) stem cells collected from the patient’s own adipose are concentrated and re-injected together with the fat. Because transplanted stem cells differentiate into new adipose tissue or vascular endothelial cells, this procedure has the advantages of a much higher fat graft survival (retention rate) and longer survival compared with common fat injection. Because of the use of the patient’s own adipose tissue, this represents a safer treatment with no concern for rejection.

How to Build a New Breast


Celution™ Breast Augmentation process for reconstructing or augmenting breasts relies on the recent discovery that human fat contains an amazing concentration of stem cells—cells that can be separated out using a centrifuge. That’s the science part. The artistry comes in when the surgeon makes tiny incisions for depositing the enriched fat cells, building a breast one dot-sized injection at a time like a 3-D pointillist. Here’s how it works.

 

brest1Step 1 Liposuction
Breast reconstruction usually starts in the abdomen, using liposuction to harvest fat cells. Each liposuction syringe holds about 60 cc (2 fluid ounces) of fat cells and takes five minutes to fill. Repairing the divot caused by an average lumpectomy requires eight to 10 syringes to get about 360 cc of fat tissue. Half the fat is used to create the volume needed to fill the divot and half is processed to isolate stem and regenerative cells. A typical augmentation requires 800 cc (27 ounces) of liposuctioned fat: Volume varies, but in one study 160 cc of injected stem-cell-enriched tissue boosted breast circumference an average of 4 centimeters (1.6 cup sizes).




brest2Step 2 Centrifugation
The liposuctioned fat is injected into the Celution System. The fat cells are then “washed” with proprietary enzymes that break down the scaffolding that holds the fat cells together. Next, a centrifuge separates the fat cells from the stem and regenerative cells, concentrating them into a pellet, which is then extracted. The pellet of cells is added back to some of the liposuctioned fat cells, producing a liquid suspension enriched with stem and regenerative cells and ready for injection.






brest3Step 3 Injection
Using a tool called the Celbrush, the surgeon repeatedly deposits the enriched cells in the breast, either at the site of a lumpectomy or throughout the breast for augmentation or repair of a mastectomy. With reconstruction patients, the tip on the brush makes tiny cuts that perforate scarred areas, transforming the bed of damaged tissue into a biological mesh. The Celbrush releases 0.5 cc of cell-enriched tissue each time the surgeon moves its control wheel. The process typically takes a couple of hours, depending on the extent of treatment. The deposited tissue bonds quickly to the existing tissue. Within 48 hours, new capillaries and blood vessels entwine through the new cells, supplying oxygen and nutrients to the now-stable tissue. The injection area isn’t painful afterward; patients go home the same day.



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